The Effect of High Temperature Roasted Coffea liberica on Physiological and Histological Structure of Mice’s Kidney

Ivolanesky Putri Widodo, Syamsurizal Syamsurizal, Diah Tri Utami

Abstract


Numerous varieties of coffee, such as robusta, arabica, gayo and etcetera, was made in order to fulfill the needs of its lovers. In Tungkal, Jambi, Liberica coffee was recently discovered and the chemical reactions during roasting process produces several components, which are caffeine, chlorogenic acid, monosaccharides and others, to create a unique flavor as the identity. Unique flavor of Liberica coffee is obtained from the high temperature roasting process and the components in coffee. This research aims to determine the effect of Liberica coffee (Coffea liberica), concentration (0, 8.000, 10.000 and 12.000 ppm/day) on the physiological and histological structure of the mice’s kidney (Mus musculus L.) for 28 days. The results was showed that kidney histological observation of fatty degeneration, tubular swelling, and pyknotic nucleus associated with percentages of renal tubular damage in the control group, P1, P2 and P3 were 0.71±0.96, 4.91±0.17, 5.82±0.21 and 9.01±0.13 indicating low damage (<50%) and liberica coffee does not affect physiological function, such as creatinine level.

Keywords : Liberica coffee, kidney, histological


Full Text:

PDF

References


Bacha, W.J.J., and Bacha, L.M., 2000, Color Atlas of Veterinary Histology, 2nd ed, Philadelphia: Lippincott Williams & Wilkins. Link

Cho, K.H., Kim, H.J., Kamanna, V.S. and Vaziri, N.D., 2010, Niacin Improves Renal Lipid Metabolism and Slows Progression in Chronic Kidney Disease, Biochim. Biophys. Acta, 1800(1), 6-15. CrossRef

Ganji, S.H., Qin, S., Zhang, L., Kammana, V.S. and Kashyap, M.L., 2009, Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells, Atherosclerosis, 202(1), 68-75. CrossRef

Helmi, A., Dillasamola, D. and Putri, W., 2016, Characterization and Sub Acute Toxicity Ethanol Extracts from Leaves of coffee Parasites (Scurrula ferruginea Jack Dance) to the activity of SGPT and Serum Creatinine Levels male white mice, Res. J. Pharm., Biol. Chem. Sci., 7(3), 2675-2683. Link

Higdon, J.V. and Frei, B., 2006, Coffee and Health: a Review of Recent Human Research, Crit. Rev. Food Sci. Nutr., 46(2), 101-123. CrossRef

Islam, M.T., Islam, M.K., Hossain, M.Z., and Wares, M.A., 2015, Kidney histotexture and serum creatinine level in response to concurrent administration of alcohol and coffee in mice, Bangladesh Vet., 32(2), 42–47. CrossRef

Ismail, M.S., Elmaadawy, A.A., Saad, H.H., and Al-Qahiz, N.M., 2015, Impacts of different preparations of coffee on body weight, serum uric acid and liver enzymes in experimental rats, J. Med. Med. Sci., 3(7): 292-300. Link

Kang, H.J., Kim, D.Y., Lee, S.M., Kim, K.H., Han, S.H., Nam, H.K., et al., 2013, Effect of Lowdose Niacin on Dyslipidemia, Serum Phosphorus Levels and Adverse Effects in Patients with Chronic Kidney Disease, Kidney Res. Clin. Pract., 32, 21–26. CrossRef

Lestari, D.Y., Isbandiyah, I., Marcianto, A.R., Savithri, F. and Rayyan, 2017, Acrylamide in Robusta Coffee on Blood Pressure, Urine Production and Renal Histopathological Change in White Male Rats, Adv. Health Sci. Res., 2, 247-253. CrossRef

Mitchell, R.N., Cotran, R.S., 2007, Jejas, Adaptasi, dan Kematian Sel. In: Kumar, V., Cotran, R.S., Robbins, S.L, ed., Buku Ajar Patologi Robbins Volume 1, 7th ed, Jakarta: EGC. pp. 3, 26-7. CrossRef

National Cholesterol Education Program (NCEP) Expert Panel on Detection, 2002, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III), Circulation, 106(25), 3143–421. PubMed

Panggabean, Y., 2017, Karakterisasi Biji Kopi Liberika (Coffea liberica) dengan Memvariasikan Suhu dalam Proses Roasting Menggunakan Metode Spectroscopy dan Scanning Calorimetry, Essay, Universitas Jambi, Jambi.

Perdana, B.M., Manihuruk, R., Ashyar, R., Heriyanti and Sutrisno, 2018, Evaluation of the Effect of Roasting Process on the Energy Transition and the Crystalline Structures of Arabica, Robusta, and Liberica Coffee from Jambi Indonesia, IOP Conf. Ser. Mater. Sci. Eng., 345, 012021. CrossRef

Price, S.A. and Wilson, L.M., 2005, Patofisiologi: Konsep Klinis Proses-proses Penyakit, 6th ed, Jakarta: EGC. Link

Sayed, A.A., Khalifa, M. and Abdel-Latif, F.F., 2012, Fenugreek Attenuation of Diabetic Nephropathy in Alloxan-diabetic Rats: Attenuation of Diabetic Nephropathy in Rats, J. Physiol. Biochem., 68(2), 263–269. CrossRef

Silbernagl, S. and Lang, F., 2007, Color Atlas of Pathophysiology, Jakarta: EGC. Link

Stefanello, N., Vieira, J. M., Schmatz, R. and Passamonti, S., 2015, Chlorogenic acid, caffeine and coffe reverse damages in liver, kidney and pancreas parameters of diabetic rats, J. Diabetes Health, 108, 214-228. Link

Umoh, I.U. and Jimmy, E.O., 2017, A comparative Histopathological Effect of Caffeinated and Decaffeinated Coffee on the Histomorphology of the Kidney of Adult Male Albino Wistar Rats, J. Pharm. Biol. Sci., 12(3), 62-66. CrossRef

Yusianto and Dwi, N., 2014, Mutu Fisik dan Citarasa Kopi Arabika yang Disimpan Buahnya Sebelum di-Pulping, Pelita Perkebunan, 30(2), 137-158. CrossRef

Zhou, J., Chan, L. and Zhou, S., 2012, Trigonelline : a Plant Alkaloid with Therapeutic Potential for Diabetes and Central Nervous System Disease, Curr. Med. Chem., 19(21), 3523-3531. CrossRef




DOI: http://dx.doi.org/10.14499/indonesianjcanchemoprev10iss1pp30-36

Copyright (c) 2019 Ivolanesky Putri Widodo

Indexed by:

               

               

      

 

Indonesian Society for Cancer Chemoprevention