Antioxidant Activity of Garcinia cf bancana Miq

Sri Hartati, Triyem Triyem, Herry Cahyana

Abstract


Guttiferron F and essential oil were isolated from extract n-hexane of Garcinia cf bancana Miq. Antioxidant activity was done by DPPH method to  n-hexane, methanol, ethyl acetate, n-butanol extracts and Guttiferron F, showed activity with IC50  24.5, 22.4, 29.2, 37.6 and 25.8 µg/mL respectively. The structure elucidation of Guttiferon F  based on spectroscopy data of IR, NMR of 1H and 13C.

Keywords: Antioxidant, Garcinia  cf bancana Miq., Essential oil and  Guttiferon-F.

Full Text:

PDF

References


Anne-Emmanuelle H., Aumon M. C., Mallet S., Dumontet V., Litaudon M., Rodeau D. and Richome P., (2004), Antioxidant from Garcinia veilardii, J Nat. Prod., 67, 707-709.

Balasubranian K. and Rajagopalan K., (1988), Xanthones from Garcinia mangostana, Structures of BR-Xanthone A and BR-Xanthone B, Phytochemistry, 27 (5), 1552 – 1554.

Burkill I. H., W. Birtwistle, Foxworthy F. W., Scrivenor J. B. and. Watsan J. G, (1935), A Dictionary of Economic Producds of the Malay Peninsula, Vol. 1, Gaverments of the Straits Settlemens And Federated.

Chi-Kuan H., Huang Y-L and Chen C-C, (2002), Gracinone E, A Xanthone Derivtive, has Potent Cytotoxic Effect Againts Hepatocellular Carcinoma Cell Lines, Planta Medica, 68, 975 – 979.

Chen S – X, Wan M. and Loh B – N , (1996), Active Constituens Against HIV-1 Protease from Garcinia mangostana, Planta Med. 62, 381-382.

Fuller R. W., John W. Blunt, Jamie L. B., John H., Cardellina H. and Michael R. Boyd (1999), Guttiferron F, the First Prenylated Benzophenone from Allablackia stuhlmannii, J. Nat. Prod., 62, 130 –132.

Gustafson K. R., John W. B., Murray H. G. M., Richard W. F., Tawnya C. McKee, John H. C. HMcMahon, J. B., Cragg G. M. and Michael R. B., (1992),The Guttiferones, HIV Inhibitory Benzophenones from, Tetrahedron, 48 (46), 10092 – 10102.

Inuma M., H. Tosa, T. Ito, T. Tanaka and Riswan S., (1996), Three New Benzophenone-Xanthone Dimers from the Root of Garcinia dulcis, Chem. Pharm. Bull. , 44 (9), 1744 – 1747.

Liao C-H, Ho C –T and Lin J -K, (2005), Effects of Garcinol on Free Radical Generation and NO Production in Embryonic Rat Cortical Neuron and Astrocytes, Biochem. and Biophsy. Res. Comm., 329, 1306 –1314.

Likhitwitauwuid K., Phadungcharoen T. and Krungkrai J., (1998), Antimalarial Xanthones from Garcinia cowa, Planta Medica, 64, 70-72.

Likhiawitayawuid K., Chanmahasthien W., Nijsiriruangrungsi and Krungkrai J., (1998), Xanthone with Antimalarial Activity from Garcinia dulcis, Planta Medica, 64, 281-282.

Molyneux, P., (2004), The Use of the stable free radical diphenylpicrylhydrazyl (DPPH) for estimating antioxidant activity, Songklanakarin J. Sci. Technol., 26 (2) : 211-219.

Odile T., Fahy J., Dumotet V., Chiaroni A., Riche C., Tri M. V. and Sěvenet T., (2000), Cytotoxic Prenylxanthone from Garcinia bracteata, J. Nat. Prod., 63 (4), 441 –446).

Permana D., Nordin HJ. Lajis, Mukram M. Mackeen, Abdul M. Ali, Norio Aimi, Kitajima M. and Takayama H., (2001), Isolation and Bioactive of Constituents of the Roots of Garcinia atroviridis, J. Nat. Prod., 64, 976 – 979.

Quan-Bin H., Lee S-F, Qiau C - P, He Z -D, Jin-Zheng, Sun H - D, and Xu H –X, (2005),Complete NMR Assignments of The Antibacterial Biflavonoid GB1 from Garcinia kola, Chem. Pharm. Bull, 53,(8) 1034- 1036.

Quan-Bin H., Wang Y –L., Ling Yang, Tso T -F, Qiao C -F, Song J -Z, Xu L -J, Chen S -L, Yang D -J, and Xu H - X, (2006), Cytotoxic Polyphrenilated Xanthone from the Resin of Garcinia hanburyi, Chem. Pharm. Bull, 54 (2) 265 – 267.

Sudpondma Y., Rukachaisirkul V.and Phongpaichit S., (2005), Antibacterial Cagec-Tetraprenylated Xanthones from fruit Garcinia hanburyi, Chem. Pharm. Bull, 53 (7), 850- 852.

Suksamrarn S., Suwanapoch N., Phakhodee W., Thauhiranlert J., Ratananukul P., Chimnoi N. and Suksamsarn A., (2003), Antibacterial Activity of Prenylated Xanthones from the Fruits of Garcinia mangostana, Chem. Pharm. Bull, 51 (7), 857 – 859.

Suksamrarn S., Komutiran O., Ratananukul P., Chimnoi N., Lartpornmatulee N. and Suksamrarn A., (2006), Cytotoxic Prenylated Xanthones from the Young Fruit of Garcinia mangostana, Chem. Parm. Bull, 54 (3), 301-305.

Terashima K., Takaya Y. and Niwa M., (2002), Powerful Antioxydative Agent Based on Garcionic Acid from Garcinia kola, Bioorg. Med. Chem., 10, 1619 –1625.

Tona L., et al., (2004), In vitro Antiplasmodial Activity of Extracts and Fraction from Seven Medicinal Plants Use in The Democratic Republic of Congo, J. of Ethno. Pharm. 93, 27-32.

Vatcharin R., Todpetch K., Watthanaphanit A, Saengsanae N. and Phongpaichit S., (2005), An Antibacterial Biphenyl Derivative from Garcinia bancana Miq, J. Nat. Prod., 68, 1218 – 1221.

Vatcharin R., Pharm W., Sudpindma Y., and Phongpaichit S. (2005), An Antibacterial Biphenyl Derivative from Garcinia bancana Miq., Chem. Pharm. Bull., 53 (3), 342-343.

Withmore M. A. 1973. Tree forest of Malaya. Malaysia Forest Department. Ministry of Primary Industries. Logman. P. 206.

Xu Y- J, , S. C.Yip, Kosela S., Fitri E., Hanafi M., Goh S. H. and Sim K. Y., (2000), Novel Cytotoxic, Polyphrenylated Heptacyclic Xanthonoids from Indonesian Garcinia gaudichaudii (Guttiferae), Org. Let., 2 (24), 3945-3948.

Yamaguchi F., Saito M. O., Ariga T., Yoshimura Y. and Nakazawa H., (2000), Free Radical Scavenging Activity and Antiulcer Activity from Garcinia indica Fruit Rind, J. Agric. Food Chem., 48, 2320 –3225.




DOI: http://dx.doi.org/10.14499/indonesianjcanchemoprev1iss2pp85-91

Copyright (c) 2017 Indonesian Journal of Cancer Chemoprevention

Indexed by:

               

               

      

 

Indonesian Society for Cancer Chemoprevention